ESPU Congress 2017 - Abstract book

19–22 APRIL, 2017, BARCELONA, SPAIN

13:48–13:51

S1-7 (PP)

MALE INFANTS WITH HYPOSPADIAS OR CRYPTORCHIDISM

DO NOT SHOW A DIFFERENT INDEX FINGER/RING FINGER

RATIO THAN NORMAL BOYS

Ursula TONNHOFER

, Doris HEBENSTREIT

, Martin METZELDER

and Alexander SPRINGER

1) Medical University Vienna, Paediatric Urology, Vienna, AUSTRIA - 2) Wilhelminenspital der Stadt Wien, Department

of Urology, Vienna, AUSTRIA - 3) Medical University Vienna, Department of Pediatric Surgery, Vienna, AUSTRIA

PURPOSE

Studies have shown that the index finger/ring finger ratio (2/4DR) is sexually dimorphic (smaller

in male than female). It is believed that this represents different exposure to androgens in utero.

Pathogenesis of hypospadias and undescended testis (UDT) is also closely linked to androgen

action during pregnancy. In this study, we sought to determine if there are any differences in infants

with hypospadias and UDT and controls.

MATERIAL AND METHODS

Patients were enrolled prospectively. Prior to surgery (under anesthesia) the length of the index fin-

ger and ring finger on both hands were measured using a standard caliper (from proximal crease to

the tip of the finger). The method of measurement has been proven for inter-observer reproducibility

before (Abbo et al., 2015). The groups were chosen to be homogeneous in age and children above

5 years of age were excluded. Hypospadias were classified according to the SIU classification.

RESULTS

The were 208 participants: 102 controls (mean 1.37, +/- 1.41 years), 41 mild hypospadias (mean

1.75, +/- 1.31 years), 20 severe hypospadias (mean 1.22, +/- 0,78 years), and 45 UDT (mean

1.54, +/- 1.16 years). Right hand: 2/4DR controls: 0,950 +/-0,062, mild hypospadias: 0,964+/-0,050,

severe hypospadias 0,950+/-0,050, UDT 0,952+/-0,040. Left hand: 2/4DR controls: 0,952+/-0,060,

mild hypospadias: 0,928+/-0,155, severe hypospadias 0,948+/-0,044, UDT 0,955+/-0,049. There

were no significant differences in any of the sub groups.

CONCLUSIONS

In our study (infants under the age of 5 years) we could not show any differences in the 2/4 digit

ratio for children with mild hypospadias, severe hypospadias, UDT, and controls. These findings are

in contrast to the literature which has shown significant differences in male/female, hypospadias,

UDT, male social behavior, testosterone levels and other items. One explanation could be that the

2/4 digit ratio dimorphism is not well developed in infants.

13:51–14:12

Discussion