ESPU Congress 2017 - Abstract book

19–22 APRIL, 2017, BARCELONA, SPAIN

RESULTS

Four died in infancy and four (2%) were diagnosed with cancer of the urinary bladder. Thirteen

(7%) had psychiatric diagnosis, and sensory neurogenic hearing disorders were noted in five cases

(3%), which may indicate an association with the 22q11 duplication syndrome. A generally high

educational level was identified and registered partnership data was comparable to controls. Cases,

of both sexes, conceived significantly less biological children, though mean age at first child did not

differ.

CONCLUSIONS

The mortality and comorbidity rate was low. The educational level was high overall and partner-

ship formations were comparable to controls. However, both male and female cases conceived

significantly less children than controls.

10:56–10:59

S7-5 (PP)

THE MACROSCOPIC AND MICROSCOPIC APPEARANCE

OF THE BLADDER TEMPLATE IN EXSTROPHY PATIENTS

UNDERGOING DELAYED EXSTROPHY REPAIR

David KEENE

, Cezar NICOARA

, Vytis KAZLAUSKAS

, Alessandra SCALAS

Melanie NEWBOULD

and Raimondo Maximilian CERVELLIONE

1) Royal Manchester Children’s Hospital, Paediatric Urology, Manchester, UNITED KINGDOM - 2) Royal Manchester

Children’s Hospital, Paediatric Histopathology, Manchester, UNITED KINGDOM

PURPOSE

To correlate the macroscopic appearance of bladder templates in classic exstrophy with the histo-

logical features of the polyps after resection.

MATERIAL AND METHODS

Since 2007 the authors have routinely delayed BE closure to 3-6 months of age regardless of the

size and quality of the bladder template. The bladder templates were photographed and classified

prior to BE closure using the following criteria: Group A -smooth, no polyps, Group B 1-5 polyps,

Group C>6 polyps. Fisher’s exact test compared the proportion of patients in each group with

intestinal metaplasia. Bladder polyps, if present, are removed prior to closure and sent for histologi-

cal evaluation.

RESULTS

Sixty-three patients with classic bladder exstrophy patients were classified using the above polyp

score; 21 patients (33%) had a smooth bladder template, 42 patients (66%) had a polypoid bladder

template (29 group B, 13 group C). Forty-one of the 42 patients with polyps had polyp resection prior

to BE closure. Two patients had a second polypectomy prior to BE closure. A significantly higher

proportion of patients in group C demonstrated intestinal metaplasia within the resected polyps

compared to group B (61% vs 17%) p=0.009.

Group

Smooth

Moderately

polypoid

Severely

polypoid

Number of patients

Median age at time of polypectomy (months)

4.0(2.5-6.4)

4.7(1.7-6.8)

Number of polypectomy procedures

Median age at BE closure (months)

4.1(3.5-5.6)

4.8(3.7-6.8)

6.5(4.9-7.9)