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19–22 APRIL, 2017, BARCELONA, SPAIN
MATERIAL AND METHODS
The medical records of children who had undergone AGC between 1992 and 2000 were reviewed
retrospectively. All of the patients were recontacted by telephone.
RESULTS
Eleven patients underwent a AGC at a median age of 11years (range 6.5-14). The underlying diag-
nosis included myelomeningocele (n=4), bladder exstrophy (n=4), posterior urethral valves (n=1),
irradiated bladder (n=1) and Prune Belly syndrome (n=1). Median follow-up was 17 years (range
15-19.5). Renal function was preserved or improved in 63% of patients and 80% of patients were
dry after AGC. Seven (63%) patients reported symptoms linked to haematuria-dysuria syndrome,
which was resistant to treatment in one case and requiring excision of the gastric patch. Three of the
11 patients (23%) developed a tumour on the gastric patch after a median delay of 20years (range
11-22). All had gastric adenocarcinoma of which two were metastatic at the time of diagnosis. Seven
of the 11 (63%) patients underwent excision of the gastric patch after 11years (range 8.5-20.5).
CONCLUSIONS
We confirmed that the majority of patients undergoing AGC had preservation of their renal function
and were continent. However, long-term, AGC was associated with a significant risk of malignant
transformation and a high rate of surgical re-intervention involving removal of the gastric patch.
These results question the use of this technique for bladder augmentation, irrespective of the
indication.