ESPU Congress 2018 - Abstract Book

165 11–14 APRIL, 2018, HELSINKI, FINLAND S22: LOWER URINARY TRACT 2 Moderators: Gundela Holmdahl (Sweden), Abraham Cherian (UK) ESPU Meeting on Saturday 14, April 2018, 09:10–09:54 09:10–09:13 S22-1 (PP) ★ THERAPEUTIC EFFECTS OF MINIRIN IN MONOSYMPTOMATIC ENURESIS TREATMENT DEPENDING ON PATIENTS' AGE Sasa MILIVOJEVIC  1 , Jelena MILIN LAZOVIC  2 and Zoran RADOJICIC  3 1) University Children's Hospital Belgrade, Paediatric Surgery, Belgrade, SERBIA - 2) Faculty of Medicine, University of Belgrade, Institute for Medical Statistics and Informatics, Belgrade, SERBIA - 3) University Children's Hospital Belgrade, Paediatric Urology, Belgrade, SERBIA PURPOSE To test the therapeutic effects of Minirin in monosymptomatic enuresis treatment depending on patients’ age. MATERIAL AND METHODS The prospective research was carried out in the 2014–2017 period, during which 89 patients were observed who were treated with Minirin due to the previously diagnosed monosymptomatic enu- resis. The patients were divided into two age groups. The first group consisted of 43 patients age 5 to 7, with the average age of 5.6 ± 0.5, out of whom 35 (81.4 %) were boys, and 8 (18.6 %) were girls. The second group consisted of 46 patients age over 7 to 12, with the average age of 9.7 ± 1.6, out of whom 30 (65.2 %) were boys, and 16 (34.8 %) were girls. There was no statistically relevant difference according to sex (p=0.086). After the 3-month treatment, all the patients in both groups were tested for the effects of Minirin in monosymptomatic enuresis treatment. RESULTS The average enuresis frequency in the first group before therapy was 26.0 ± 6.2 per month, whereas the average enuresis frequency after therapy was 11.0 ± 8.0 per month (p=0.040). The average enuresis frequency in the second group before therapy was 23.1 ± 6.2 per month, whereas the average enuresis frequency after therapy was 3.8 ± 3.6 per month (p=0.036). ANOVA data analysis of repeated measurements has indicated that there is a statistically relevant interaction between the groups (p=0.006), i.e. enuresis frequency decreases considerably more in the second group. CONCLUSIONS Monosymptomatic enuresis treatment with Minirin is noticeably more effective with patients over 7 years of age.