ESPU Congress 2018 - Abstract Book

111 11–14 APRIL, 2018, HELSINKI, FINLAND 08:29–08:32 S13-6 (PP) ★ ASSESSMENT OF UROFLOWMETRY PARAMETERS IN HEMATOPOIETIC CELL TRANSPLANTATION RECIPIENTS COMPLICATED BY HEMORRHAGIC CYSTITIS Sahar EFTEKHARZADEH  1 , Mehrnoosh SAMAEI  1 , Seyed Farshad SEYED TAHER  1 , Amirali HAMIDIEH  1 and Abdol-Mohammad KAJBAFZADEH  2 1) Children's Hospital Medical Center, Tehran University of Medical Sciences, Pediatric Urology Research Center, Tehran, ISLAMIC REPUBLIC OF IRAN - 2) Children's Hospital, Urology, Tehran, ISLAMIC REPUBLIC OF IRAN PURPOSE Hemorrhagic Cystitis (HC) constitutes a common yet serious complication in hematopoietic cell transplantation (HCT) recipients; although preventive measures against HC are taken still it could lead to severe morbidity and mortality in these patients. In this study we aim to assess value of uroflowmetry parameters in prediction of HC occurrence. MATERIAL AND METHODS Thirty-seven patients with a mean±SD age of 9.98±3.77 years, who received HCT from July 2011 till July 2015 were randomly included in this prospective study. Patients' uroflowmetry parameters in the day of transplantation, 1 day after transplantation and 15 days after transplantation were recorded. In case of accessibility uroflowmetry was performed at the time of HC as well. RESULTS Eighteen patients (48.6 %) faced HC 38.44±28.60 days following HCT. Uroflowmetry parameters were compared among patients who suffered from HC and those who did not. Analysis of data indicates that voided volume and average flow rate on the 15 th days after transplantation were significantly higher in patients who faced HC(p<0.05), also it indicates that distribution of voided volume and average flow rate on the 15 th days after transplantation differs significantly between who suffered from HC and those who did not (p<0.05). Kendall's tau and Spearman's (rho) rank correlation coefficient tests also indicate significant correlation between mentioned two parameters and occurrence of cystitis (p<0.05). CONCLUSIONS This study suggests that uroflowmetry parameters could be valuable in predicting HC occurrence; however, further studies with larger populations are needed to confirm its predictive values.