ESPU Congress 2018 - Abstract Book

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98 29th CONGRESS OF THE ESPU
16:25–16:28
S11-6 (PP)
★ NON-MODIFIABLE PREDICTIVE FACTORS FOR
COMPLICATIONS IN THE DUTCH HYPOSPADIAS STUDY
Goedele BECKERS1 , Fred VAN DER TOORN2, Keetje DE MOOIJ3, Robert DE
GIER4, Rien NIJMAN5 , Piet CALLEWAERT6, Martijn STEFFENS7, Eric VAN DER
HORST8 , Piet HOEBEKE9, Frank FROELING10, Mark WILDHAGEN11 and Katja P.
WOLFFENBUTTEL12
1) VU University Medical Center, Paediatric Urology, Amsterdam, NETHERLANDS - 2) Sophia's Children Hospital,
Pediatric Urology, Rotterdam, NETHERLANDS - 3) University Children's Hospital UMC, Pediatric Renal Center, Utrecht,
NETHERLANDS - 4) Radboud University Medical Center, Pediatric Urology, Nijmegen, NETHERLANDS - 5) University
Medical Center Groningen, Pediatric Urology, Groningen, NETHERLANDS - 6) Maastricht University Medical Center,
Pediatric Urology, Maastricht, NETHERLANDS - 7) Isala Hospital Zwolle, Pediatric urology, Zwolle, NETHERLANDS -
8) VU University Medical Center, Pediatric Urology, Amsterdam, NETHERLANDS - 9) University Hospital Gent, Pediatric
Urology, Gent, BELGIUM - 10) Haga Hospital The Hague, Pediatric Urology, Den Haag, NETHERLANDS - 11) Erasmus
Medical Center, Unit of Trials and Research Coordination, Rotterdam, NETHERLANDS - 12) Sophia's Children Hospital,
Pediatric Urology, Rotterdam, NETHERLANDS
PURPOSE
The position of the meatus and of the division of the corpus spongiosum (DCS) are considered
predictive factors for the outcome of hypospadias surgery. We determine the odds of non-modifiable
factors registered in the Dutch Hypospadias Study database (DHyS) for postoperative complications.
MATERIAL AND METHODS
The DHyS contains prospective data of 1233 evaluable patients. The relation between pre- and
dysmaturity, meatal position, position of DCS, preoperative penile length, penile curvature (more
than 30 degrees after deglovement) and complications 6 months after first correction were investi-
gated with logistic regression. Categorical variables were coded from less to more severe.
RESULTS
46(5.4 %) children were born pre- and/or dysmaturely: median age at birth gestational week
35(IQR 32–37), birth weight 1862grams(IQR 1200–2500). Birth weight of all other children was not
registered.
For all cases, meatal position was 291 glanular, 757 coronal/distal shaft, 83 midschaft, 56 proximal
and 46 penoscrotal. The position of DCS was: 681 distal shaft, 392 midshaft, and 160 proximal
shaft. Preoperative penile length was 43 mm(IQR 35–50). Penile curvature was seen in 894 cases.
185 children had no urethraplasty. 250 children(20 %) had a postoperative complication.
Univariate and multivariate analysis of significant outcome variables are shown. Pre-or dysmaturity
and penile length at operation were not significant for outcome(p=0.538 and p=0.581 resp).
Univariate analysis Multivariate analysis
Odds CI Odds CI
Meatal position 1.652 1.537–1.775 1.415 1.281–1.562
Position division corpus spongiosum 1.835 1.667–2.020 1.346 1.180–1.534
Penile curvature 1.587 1.363–1.848 0.996 0.910–1.090
CONCLUSIONS
Meatal position and position of DCS are the only contributing non-modifiable predictive factors for
complications after hypospadias surgery. Pre- or dysmaturity, penile length and penile curvature did
not influence outcome significantly.