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78
29
th
CONGRESS OF THE ESPU
11:57–12:00
S8-3 (PP)
PSYCHIATRIC OUTCOME IN MEN WITH HYPOSPADIAS
Lisa ÖRTQVIST
1
, Hedvig ENGBERG
2
, Anna STRANDQVIST
2
, Anna
NORDENSTRÖM
2
, Gundela HOLMDAHL
3
, Agneta NORDENSKJÖLJD
4
and
Louise FRISÉN
5
1) Department of pediatric surgery, Stockholm, SWEDEN - 2) Women and Children health, Stockholm, SWEDEN -
3) University Hospital Sahlgrenska Academy, Women's and Children's Health, Gothenburg, SWEDEN - 4) Karolinska
Institutet, Department of Women's and Children's Health and Centre for Molecular Medicine, Stockholm, SWEDEN
- 5) Karolinska Institutet, Child and Adolescent Psychiatry Research Centre, Department of Psychology, Stockholm,
SWEDEN
PURPOSE
Population studies have shown an increased risk for neurodevelopmental disorders in males born
with hypospadias. We aimed to investigate psychiatric morbidity in men with hypospadias in a ret-
rospective clinical cohort study.
MATERIAL AND METHODS
One hundred and sixty-seven men born with hypospadias, with a mean age of 34 years, completed
self-rating scales screening for depressive, anxiety, and obsessive-compulsive symptoms (CPRS-
S-A), as well as symptoms of ADHD (ASRS-short). Thirty-three of these men also underwent an
interview screening for psychiatric morbidity (MINI). Their results were compared with those of
age-matched population-derived controls.
Numerical outcome variables were analyzed with the Mann Whitney-U test and one-way ANOVA.
Chi-square or Fisher’s exact test was used for qualitative data. P<0.05 was considered significant.
RESULTS
There were no significant differences regarding symptoms of ADHD, neither affective symptoms
between patients and controls. Seven patients (21 %) and 10 controls (21 %) reported current or
previous psychiatric symptoms (p=NS). The distribution did not differ significantly between the dif-
ferent severity groups of hypospadias.
CONCLUSIONS
These results do not support an increase in psychiatric morbidity in men with hypospadias. In order
to assure that small differences are found, a larger study population would be necessary.