ESPU Congress 2018 - Abstract Book

11–14 APRIL, 2018, HELSINKI, FINLAND

09:39–09:42

S6-2 (PP)

ROLE OF URINARY BIOMARKERS IN CORRELATION

TO DIURETIC RENOGRAM IN CHILDREN WITH URETERO-

PELVIC JUNCTION OBSTRUCTION UNDERGOING

PYELOPLASTY

Waleed DAWOOD

, Haitham BADAWY

, Samir ORABI

, Ahmed FAHMY

Mohamed YOUSSEF

, Reham ABDELHALEEM

and Mohamed ABDELRAZEK

1) Alexandria faculty of Medicine, Faculty of Medicine, Alexandria, EGYPT - 2) ALEXANDRIA UNIVERSITY, UROLOGY,

Alexandria, EGYPT - 3) ALEXANDRIA UNIVERSITY, CILINICAL PATHOLOGY, Alexandria, EGYPT

PURPOSE

Urinary biomarkers as KIM and NGAL could be used as predictors for structural and functional

kidney damage resulting from UPJO, thus can replace diuretic renogram. Our study was to cor-

relate urinary KIM and NGAL levels pre and postoperatively and with the DRF of the affected kidney.

MATERIAL AND METHODS

A prospective controlled study was done in 30 patients treated with unilateral dismembered py-

eloplasty from 2016 to 2017. Urine samples were obtained preoperatively, intraoperatively, and

6 months postoperatively. A control group consist of 10 healthy children.

RESULTS

There was an increase in uKIM and uNGAL levels in pre and intraoperative urine samples (4.85 ng/

ml, 5.40 ng/ml for NGAL, 0.32 ng/ml, 0.38 ng/ml for KIM), a significant reduction in these levels

was found after surgical repair of UPJO (1.5 ng/ml for NGAL, 0.09 ng/ml for KIM), these high levels

preoperatively don't significantly correlate with the DRF, also these levels preoperatively was signifi-

cantly higher than that from control group concerning uNGAL (0.60 ng/ml) but insignificantly higher

than that from control group concerning uKIM (0.20 ng/ml).

CONCLUSIONS

Preoperative uKIM-1and uNGAL levels were increased significantly in patients with UPJO undergo-

ing pyeloplasty, these high levels don't significantly correlates with diuretic renogram, and also there

was a significant reduction in their concentrations in the postoperative follow-up.

09:42–09:45

S6-3 (PP)

POSSIBLE PREDICTIVE FACTORS FOR A SAFE PRENATAL

FOLLOW-UP OF FETUSES WITH HYDONEPHROSIS

Abdurrahman ONEN

Onen Cocuk Urolojisi Merkezi, Paediatric Surgery, Diyarbakir, TURKEY

PURPOSE

Introduction: To determine the factors affecting the resolution of hydronephrosis, create a follow-up

protocol to predict the probability of pre-and/or postnatal resolution, and to refine criteria for a safe

follow-up of fetuses with hydronephrosis.