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147
11–14 APRIL, 2018, HELSINKI, FINLAND
CONCLUSIONS
Bladder capacity in PUV, either normal or abnormal, does not affect bladder emptying and does not
correlate with renal impairment.
1 Austin PF et al. J Urol 2014; 191: 1863–1865
16:08–16:23
Discussion
16:23–16:26
S19-6 (PP)
PRELIMINARY EXPERIENCE WITH INSTILLATION
OF TRIAMCINOLONE ACETONIDE INTO THE URETHRA
FOR IDIOPATHIC URETHRITIS: A PROSPECTIVE PILOT
STUDY
Junaid ASHRAF, Anna RADFORD, Alexander TURNER and Ramnath
SUBRAMANIAM
Leeds Children's Hospital, Department of Paediatric Urology, Leeds, UNITED KINGDOM
PURPOSE
Idiopathic Bulbar Urethritis (IBU) is characterised by haematuria +/- dysuria without infection.
Symptoms result from inflammation of the bulbar urethra, distal to external sphincter. IBU is difficult
to manage and there is no recommended therapy. The aim of the study was to determine whether
instillation of triamcinolone acetonide is a useful treatment of IBU and its’ associated complications.
MATERIAL AND METHODS
Data was prospectively collected, for 38 months, on 28 consecutive patients presenting with terminal
haematuria or blood spotting +/- dysuria to a paediatric urology unit. Visual confirmation of IBU was
obtained cystoscopically and 80 mg of triamcinolone was instilled to the inflamed area under direct
vision using an open-ended ureteral catheter. Follow-up telephone interviews, to assess symptom
persistence and side-effects, were performed at six weeks post-intervention.
Symptoms resolution was the primary outcome. Repeat cystoscopic assessment +/- triamcinolone
instillation was recorded, as was the occurrence of complications.
RESULTS
Median age 12 years (range: 9–16). Mean symptom duration 16 months (range: 6–30). Normal
baseline laboratory blood tests, urine cultures and ultrasound assessments were seen in all;
therefore, none were excluded on the basis of a known pathology. The mean follow-up period was
28 months (range: 4–42).
12 patients (42.85 %) required at least one further treatment. Overall complete or partial resolution
was reported in 21/28 (75 %). No side effects were reported.
CONCLUSIONS
This prospective series demonstrates that intra-urethral instillation of triamcinolone seems to be
promising treatment option to alleviate inflammatory symptoms in majority of cases of idiopathic
urethritis.